AIM: the role of exercise (aerobic and resistance) training as a therapeutic strategy for the treatment and prevention of AD ADDED VALUE: The main protective mechanism on brain function modulated by physical exercise by examining both human and animal studies and the role of exercise in the modulation of amyloid b turnover, inflammation, synthesis and release of neurotrophins, and improvements in cerebral blood flow. The study is an exetnsive review of the effects of physical exercise (aerobic and strength training) on brain aging, the main mechanisms activated at the brain level, and the protective role on Dementia.

ECArTE is a consortium of Universities. Its primary purpose is to represent and encourage the development of the Arts Therapies and Arts Therapies education in Europe, in particular the courses offering nationally validated and professionally recognised training for Arts Therapists. (The Arts Therapies include art therapy, dance therapy, dramatherapy and music therapy). ECArTE was founded in 1991 by the Universities of Hertfordshire, Münster, Nijmegen and Paris. Currently it comprises 34 member institutions from 13 European countries.

Think Pink is the national campaign for fight breast cancer and fights daily for people with the disease and their families. It meets four objectives: -Inform -Raise awareness -Support specific research in the context of breast cancer -Providing help with health care costs before and after illness

The literature regarding exercise for people with established anxiety disorders is equivocal. To address this issue, we conducted a systematic review and meta-analysis investigating the benefits of exercise compared to usual treatment or control conditions in people with an anxiety and/or stress-related disorders. Major electronic databases were searched from inception until December/2015 and a random effect meta-analysis conducted. Altogether, six randomized control trials (RCTs) including 262 adults (exercise n=132, 34.74 [9.6] years; control n=130, 37.34 [10.0] years) were included.

Objective: This study aimed to establish an international consensus on physical therapists' beliefs, potential benefits and practices in the use of physical activity in schizophrenia. Method: All members of the International Organization of Physical Therapists in Mental Health were invited to take part in a cross‐sectional online survey. All data were analysed using descriptive statistics and quantitative content and/or thematic analysis.

Aim: To obtain an international perspective of mental health physiotherapists on their role within the treatment of individuals diagnosed with schizophrenia. Method: A cross-sectional survey of members of the International Organisation of Physical Therapists interested in mental health (IOPTMH) was undertaken. Free text responses to open-ended questions were analysed with a thematic analysis.

Objective : To evaluate the effect of behavioral techniques and physical exercise on psychosocial functioning and health‐related quality of life (HRQoL) outcomes in breast cancer patients and survivors. Methods : A meta‐analysis was carried out to quantify the effects of behavioral and exercise interventions on fatigue, depression, anxiety, body‐image, stress and HRQoL. Summary effect sizes and standard errors were calculated. The presence of publication bias was explored and sensitivity analyses were performed to identify possible sources of heterogeneity.

The literature regarding exercise for people with established anxiety disorders is equivocal. To address this issue, we conducted a systematic review and meta-analysis investigating the benefits of exercise compared to usual treatment or control conditions in people with an anxiety and/or stress-related disorders. Major electronic databases were searched from inception until December/2015 and a random effect meta-analysis conducted. Altogether, six randomized control trials (RCTs) including 262 adults (exercise n=132, 34.74 [9.6] years; control n=130, 37.34 [10.0] years) were included. Exercise significantly decreased anxiety symptoms more than control conditions, with a moderate effect size (Standardized Mean Difference=−0.582, 95%CI −1.0 to −0.76, p=0.02).

Objectives: To support return to work (RTW) among cancer patients, a multidisciplinary rehabilitation programme was developed which combined occupational counselling with a supervised physical exercise programme during chemotherapy. The aim was to investigate RTW rates of cancer patients and to evaluate changes in work-related quality of life and physical outcomes. Design: Longitudinal prospective intervention study using a one-group design. Setting :Two hospitals in the Netherlands. Participants: Of the eligible patients, 56% participated; 93 patients with a primary diagnosis of cancer receiving chemotherapy and on sick leave were included. Patients completed questionnaires on RTW, the importance of work, work ability (WAI), RTW self-efficacy, fatigue (MFI), and quality of life (EORTC QLQ C-30) at baseline and 6, 12 and 18 months follow-up. Before and after the exercise programme 1-repetition maximum (1RM) muscle strength and cardiorespiratory fitness (VO2 peak) were assessed.

Objective: There is evidence of more obesity among persons with depressive and depressive and anxiety disorders. However, the nature and the underlying mechanisms of the association are still unclear. This study examines the association between depressive and anxiety disorders and obesity, physical activity, and social activity, and examines whether social and physical activity are potential influencing factors in the association between depressive and anxiety disorders and obesity. Method: Cross‐sectional data were used from the Netherlands Study of Depression and Anxiety. A total of 1,854 women and 955 men aged 18–65 years were recruited from the community, general practices, and specialized mental health care. Depressive and anxiety disorders were determined with the Composite International Diagnostic Interview. Body mass index (BMI<30 kg/m2) was used to determine obesity. Physical and social activities were measured by self‐report.

Background: Depressive and anxiety disorders have shown to be associated to premature or advanced biological aging and consequently to adversely impact somatic health. Treatments with antidepressant medication or running therapy are both found to be effective for many but not all patients with mood and anxiety disorders. These interventions may, however, work through different pathophysiological mechanisms and could differ in their impact on biological aging and somatic health. This study protocol describes the design of an unique intervention study that examines whether both treatments are similarly effective in reducing or reversing biological aging (primary outcome), psychiatric status, metabolic stress and neurobiological indicators (secondary outcomes). Methods: The MOod Treatment with Antidepressants or Running (MOTAR) study will recruit a total of 160 patients with a current major depressive and/or anxiety disorder in a mental health care setting. Patients will receive a 16-week treatment with either antidepressant medication or running therapy (3 times/week). Patients will undergo the treatment of their preference and a subsample will be randomized (1:1) to overcome preference bias. An additional no-disease-no-treatment group of 60 healthy controls without lifetime psychopathology, will be included as comparison group for primary and secondary outcomes at baseline. Assessments are done at week 0 for patients and controls, and at week 16 and week 52 for patients only, including written questionnaires, a psychiatric and medical examination, blood, urine and saliva collection and a cycle ergometer test, to gather information about biological aging (telomere length and telomerase activity), mental health (depression and anxiety disorder characteristics), general fitness, metabolic stress-related biomarkers (inflammation, metabolic syndrome, cortisol) and genetic determinants. In addition, neurobiological alterations in brain processes will be assessed using structural and functional Magnetic Resonance Imaging (MRI) in a subsample of at least 25 patients per treatment arm and in all controls.

In Luxembourg, 21.6% of the population suffers from depression and 6% have moderate to severe symptoms. The main treatment options include antidepressant medication and psychotherapy, but other options such as physical activity are recommended.